

| 카탈로그 번호 | MF562014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse ADA/Adenosine deaminase Polyclonal Antibody (MF562014) is a rabbit polyclonal antibody detecting Adenosine deaminase in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 종 반응성 | Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse ADA/Adenosine deaminase (Met1-Gln352). | ||||||||
| 타겟 | Adenosine deaminase, 3.5.4.4, Adenosine aminohydrolase, Ada | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P03958 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Adenosine deaminase (ADA) is a ~39 kDa protein. Catalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine. Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4. Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion. 1. Xu, PA. et al. (2000) Biochemical and biophysical research communications 269, 749-57. PMID: 10720488 2. Mohamedali, KA. et al. (1996) Biochemistry 35, 1672-80. PMID: 8634299 3. Sideraki, V. et al. (1996) Biochemistry 35, 7862-72. PMID: 8672487 4. Sideraki, V. et al. (1996) Biochemistry 35, 15019-28. PMID: 8942668 5. Blackburn, MR. et al. (1997) Development (Cambridge, England) 124, 3089-97. PMID: 9272950 6. Apasov, SG. et al. (2001) The Journal of clinical investigation 108, 131-41. PMID: 11435465 7. Li, G. et al. (2015) Pharmacology research & perspectives 3, e00121. PMID: 26038697 | ||||||||
| 참고사항 | For research use only. |

Western blot analysis was performed using anti-ADA polyclonal antibody at ADA on various samples.
Lane 1: Jurkat cell lysate
Lane 2: MOLT-4 cell lysate
Lane 3: Mouse thymus lysate
Lane 4: Mouse stomach lysate
Lane 5: Rat spleen lysate


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