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| 카탈로그 번호 | MS942014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse Arl13b Polyclonal Antibody (MS942014) is a rabbit polyclonal antibody detecting ARL13B. Suitable for Human and Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse Arl13b (Met1-Ser241). | ||||||||
| 타겟 | ADP-ribosylation factor-like protein 13B, ADP-ribosylation factor-like protein 2-like 1, ARL13B, ARL2-like protein 1, ARL2L1 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q640N2 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | ADP-ribosylation factor-like protein 13B (Arl13b) is a ~48 kDa protein. Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B. Binds GTP but is not able to hydrolyze it; the GTPase activity remains unclear. Required to pattern the neural tube. Involved in cerebral cortex development: required for the initial formation of a polarized radial glial scaffold, the first step in the construction of the cerebral cortex, by regulating ciliary signaling. 1. Higginbotham, H. et al. (2013) Nature neuroscience 16, 1000-7. PMID: 23817546 2. Higginbotham, H. et al. (2012) Developmental cell 23, 925-38. PMID: 23153492 | ||||||||
| 참고사항 | For research use only. |
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