Anti-Mouse Thrombopoietin R/Tpo R Polyclonal Antibody (MW601014)

Name: Anti-Mouse Thrombopoietin R/Tpo R Polyclonal Antibody
Brand: abinScience
SKU: MW601014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MW601014

설명

Anti-Mouse CD110/MPL Polyclonal Antibody (MW601014) is a rabbit polyclonal antibody detecting CD110 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse CD110/MPL (Ser394-Ile483).

타겟

Thrombopoietin receptor, TPO-R, Myeloproliferative leukemia protein, Proto-oncogene c-Mpl, CD110, Mpl, Tpor

정제

Purified by antigen affinity column.

등록번호

Q08351

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Thrombopoietin receptor (CD110/MPL) is a ~69 kDa protein. Receptor for thrombopoietin that regulates hematopoietic stem cell renewal, megakaryocyte differentiation, and platelet formation. Upon activation by THPO, induces rapid tyrosine phosphorylation and activation of JAK2, providing docking sites for many signaling proteins such as STAT5, SHIP/INPP5D, GRB2, SOS1 and PI3K. In turn, These signaling cascades lead to the proliferation, survival, and differentiation of megakaryocytes, ultimately leading to increased platelet production.

1. Alexander, WS. et al. (1996) Blood 87, 2162-70. PMID: 8630375

2. Drachman, JG. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 2350-5. PMID: 9122198

3. Solar, GP. et al. (1998) Blood 92, 4-10. PMID: 9639492

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Mouse Thrombopoietin R/Tpo R Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse Thrombopoietin R/Tpo R Polyclonal Antibody (MW601014)

개요

이미지

참고 문헌

데이터시트

SDS

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