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| 카탈로그 번호 | MB805137 |
|---|---|
| 종 반응성 | Mouse |
| 응용 분야 | FCM, IF |
| 숙주 종 | Rat |
| 클론성 | Monoclonal |
| 이소타입 | IgG2b |
| 클론 ID | FD441.8 |
| 접합 | APC |
| 타겟 | CD11A, Leukocyte function-associated molecule 1 alpha chain, Leukocyte adhesion glycoprotein LFA-1 alpha chain, LFA-1A, CD11 antigen-like family member A, CD11a, ITGAL, Integrin alpha-L |
| 내독소 수준 | Please contact with the lab for this information. |
| 관련 제품 | Rat IgG2b, kappa Recombinant Isotype Control Antibody (ES26-5E12.4), APC |
| 등록번호 | P24063 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 배경 | Integrin alpha-L (CD11a/ITGAL) is a ~128 kDa protein. Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is a receptor for F11R. Integrin ITGAL/ITGB2 is a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes. Contributes to natural killer cell cytotoxicity. 1. Kaufmann, Y. et al. (1991) Journal of immunology (Baltimore, Md. : 1950) 147, 369-74. PMID: 2051027 2. Swaim, CD. et al. (2017) Molecular cell 68, 581-590.e5. PMID: 29100055 3. Liu, Z. et al. (2006) Blood 107, 1063-9. PMID: 16234355 4. Jiang, E. et al. (2014) Arteriosclerosis, thrombosis, and vascular biology 34, 34-43. PMID: 24158516 5. Bose, TO. et al. (2014) Journal of immunology (Baltimore, Md. : 1950) 193, 2863-72. PMID: 25108025 |
| 참고사항 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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