



| 카탈로그 번호 | MY392307 |
|---|---|
| 브랜드 | abinScience |
| 종 반응성 | Human, Mouse, Bovine, Hamster |
| 응용 분야 | ELISA, FCM |
| 숙주 종 | Mouse |
| 클론성 | Monoclonal |
| 이소타입 | IgG2a, kappa |
| 클론 ID | POM1 |
| 테스트된 응용 분야 | WB |
| 타겟 | Major prion protein, PrP, PrP27-30, PrP33-35C, CD230, Prnp, Prn-p |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P04925 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 배경 | Major prion protein (CD230/PRNP) is a ~27 kDa protein. Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. 1. Mani, K. et al. (2003) The Journal of biological chemistry 278, 38956-65. PMID: 12732622 2. Steele, AD. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 3416-21. PMID: 16492732 3. Laurén, J. et al. (2009) Nature 457, 1128-32. PMID: 19242475 4. Singh, A. et al. (2009) PloS one 4, e6115. PMID: 19568430 |
| 참고사항 | For research use only. |

Detects Human CD230/PRNP in indirect ELISAs.

Western blot analysis was performed using anti-CD230/PRNP monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant human CD230/PRNP (Catalog No: HY392011)
Lane 2: negative control




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