

| 카탈로그 번호 | MF564014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse B7-H2 Polyclonal Antibody (MF564014) is a rabbit polyclonal antibody detecting B7-H2 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 종 반응성 | Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse CD275/ICOSLG (Glu47-Gln258). | ||||||||
| 타겟 | ICOS ligand (B7 homolog 2) (B7-H2) (B7-like protein Gl50) (B7-related protein 1) (B7RP-1) (LICOS) (CD antigen CD275) | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9JHJ8 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | ICOS ligand (CD275/ICOSLG) is a ~35 kDa protein. Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; also induces B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (Probable). During pregnancy, may function to skew the cytokine of maternal T-cells toward immunoprotective Th2 phenotype. 1. Swallow, MM. et al. (1999) Immunity 11, 423-32. PMID: 10549624 2. Yoshinaga, SK. et al. (1999) Nature 402, 827-32. PMID: 10617205 3. Ling, V. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 164, 1653-7. PMID: 10657606 | ||||||||
| 참고사항 | For research use only. |
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