Anti-Mouse CD276/B7-H3 Recombinant Antibody (m276) (MV612207)

Name: Anti-Mouse CD276/B7-H3 Recombinant Antibody (m276)
Brand: abinScience
SKU: MV612207
Price: 191 USD
Availability: InStock

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개요

카탈로그 번호	MV612207
종 반응성	Human, Mouse, Rat
응용 분야	FCM
숙주 종	Rat
클론성	Monoclonal
이소타입	IgG1, kappa
클론 ID	m276
타겟	4Ig-B7-H3, B7 homolog 3, B7-H3, B7H3, CD276, CD276 antigen, Costimulatory molecule
내독소 수준	< 10 EU/mg
순도	>95% as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	Q8VE98
형태	Liquid
저장 완충액	0.01M PBS pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경	CD276 antigen (B7-H3) is a ~34 kDa protein. Modulates T-cell-mediated immune responses and the development of acute and chronic transplant rejection. Plays a positive regulatory role in bone formation and has a dual role in the bone-immune interface. Induces antitumor immunity as it activates both acquired and innate immunity leading to natural killer cell and CD8 T-cell dependent killing of tumor cells. CD276 is the therapeutic target of omburtamab (clinical).
참고사항	For research use only.

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