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| 카탈로그 번호 | MT070207 |
|---|---|
| 종 반응성 | Human, Mouse |
| 응용 분야 | ELISA, FCM |
| 숙주 종 | Rat |
| 클론성 | Monoclonal |
| 이소타입 | IgG1, kappa |
| 클론 ID | YW64.3 |
| 타겟 | NRP1, Neuropilin-1, VEGF165R, NRP, CD304, Vascular endothelial cell growth factor 165 receptor |
| 내독소 수준 | Please contact with the lab for this information. |
| 순도 | >95% as determined by SDS-PAGE. |
| 정제 | Protein A/G purified from cell culture supernatant. |
| 등록번호 | P97333 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| 배경 | Neuropilin-1 (CD304/NRP1) is a ~103 kDa protein. Receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. Mediates the chemorepulsant activity of semaphorins. Recognizes a C-end rule (CendR) motif R/KXXR/K on its ligands which causes cellular internalization and vascular leakage. Binds to semaphorin 3A (SEMA3A), the PLGF-2 isoform of PGF, the VEGF165 isoform of VEGFA and VEGFB. Coexpression with KDR results in increased VEGF165 binding to KDR as well as increased chemotaxis. 1. He, W. et al. (2015) Nature 526, 710-4. PMID: 26503042 |
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Mouse CD304/NRP1 Antibody (YW64.3)
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