Anti-Mouse CD322/JAM2 Polyclonal Antibody (MX993014)

Name: Anti-Mouse CD322/JAM2 Polyclonal Antibody
Brand: abinScience
SKU: MX993014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MX993014

설명

Anti-Mouse CD322/JAM2 Polyclonal Antibody (MX993014) is a rabbit polyclonal antibody detecting CD322 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse CD322/JAM2 (Arg36-Asn236).

타겟

JAM-B, VEJAM, Junctional adhesion molecule B, JAM2, VE-JAM, JAM-2, C21orf43, Vascular endothelial junction-associated molecule, Junctional adhesion molecule 2, CD322

정제

Purified by antigen affinity column.

등록번호

Q9JI59

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Junctional adhesion molecule B (CD322/JAM2) is a ~33 kDa protein. Junctional adhesion protein that mediates heterotypic cell-cell interactions with its cognate receptor JAM3 to regulate different cellular processes. Plays a role in homing and mobilization of hematopoietic stem and progenitor cells within the bone marrow. At the surface of bone marrow stromal cells, it contributes to the retention of the hematopoietic stem and progenitor cells expressing JAM3. Plays a central role in leukocytes extravasation by facilitating not only transmigration but also tethering and rolling of leukocytes along the endothelium. Tethering and rolling of leukocytes are dependent on the binding by JAM2 of the integrin alpha-4/beta-1.

1. Lamagna, C. et al. (2005) Molecular biology of the cell 16, 4992-5003. PMID: 16093349

2. Arcangeli, ML. et al. (2011) Blood 118, 4609-19. PMID: 21868569

3. Arcangeli, ML. et al. (2014) Stem cells (Dayton, Ohio) 32, 1043-54. PMID: 24357068

4. Ludwig, RJ. et al. (2005) The Journal of investigative dermatology 125, 969-76. PMID: 16297198

5. Ludwig, RJ. et al. (2009) Immunology 128, 196-205. PMID: 19740376

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Mouse CD322/JAM2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse CD322/JAM2 Polyclonal Antibody (MX993014)

개요

이미지

참고 문헌

데이터시트

SDS

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