Anti-Mouse TIM-1/KIM-1/HAVCR1 Polyclonal Antibody (MV277014)

Name: Anti-Mouse TIM-1/KIM-1/HAVCR1 Polyclonal Antibody
Brand: abinScience
SKU: MV277014
Price: 168 USD
Availability: InStock

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사양:

50ug
100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MV277014

설명

Anti-Mouse CD365/KIM-1/TIM-1/HAVCR1 Polyclonal Antibody (MV277014) is a rabbit polyclonal antibody detecting HAVCR1. Suitable for Mouse.

종 반응성

Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse CD365/KIM-1/TIM-1/HAVCR1 (Tyr22-Gly237).

타겟

CD365, HAVCR1, HAVcr-1, Hepatitis A virus cellular receptor 1, KIM-1, KIM1, Kidney injury molecule 1, T-cell immunoglobulin and mucin domain-containing protein 1, T-cell immunoglobulin mucin receptor 1, T-cell membrane protein 1, TIM, TIM-1, TIM1, TIMD-1, TIMD1

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

Q5QNS5

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Hepatitis A virus cellular receptor 1 homolog (CD365/KIM-1) is a ~33 kDa protein. Phosphatidylserine receptor that plays an important functional role in regulatory B-cell homeostasis including generation, expansion and suppressor functions. As P-selectin/SELPLG ligand, plays a specialized role in activated but not naive T-cell trafficking during inflammatory responses. Controls thereby T-cell accumulation in the inflamed central nervous system (CNS) and the induction of autoimmune disease. Also regulates expression of various anti-inflammatory cytokines and co-inhibitory ligands including IL10. Acts as a regulator of T-cell proliferation.

1. Ding, Q. et al. (2011) The Journal of clinical investigation 121, 3645-56. PMID: 21821911

2. Yeung, MY. et al. (2015) American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 15, 942-53. PMID: 25645598

3. Xiao, S. et al. (2020) Cell reports 32, 107892. PMID: 32668241

4. Angiari, S. et al. (2014) Immunity 40, 542-53. PMID: 24703780

5. Xiao, S. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 1602-8. PMID: 25582854

6. Meyers, JH. et al. (2005) Nature immunology 6, 455-64. PMID: 15793576

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Mouse TIM-1/KIM-1/HAVCR1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse TIM-1/KIM-1/HAVCR1 Polyclonal Antibody (MV277014)

개요

이미지

참고 문헌

데이터시트

SDS