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| 카탈로그 번호 | MV571137 |
|---|---|
| 종 반응성 | Human, Mouse, Monkey |
| 응용 분야 | ELISA, FCM |
| 숙주 종 | Rat |
| 클론성 | Monoclonal |
| 이소타입 | IgG1, kappa |
| 클론 ID | 21H3RK |
| 접합 | APC |
| 타겟 | Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4 |
| 내독소 수준 | Please contact with the lab for this information. |
| 관련 제품 | Rat IgG1, kappa Recombinant Isotype Control Antibody (ES26-14D1.11), APC |
| 등록번호 | Q9JI71 |
| 형태 | Liquid |
| 저장 완충액 | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
| 안정성 및 저장 | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| 배경 | Delta-like protein 4 (DLL4) is a ~74 kDa protein. Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. 1. Yoneya, T. et al. (2001) Journal of biochemistry 129, 27-34. PMID: 11134954 2. Luo, H. et al. (2012) Proceedings of the National Academy of Sciences of the United States of America 109, E553-62. PMID: 22323600 |
| 참고사항 | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |
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