

| 카탈로그 번호 | MP294014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse EGFLAM Polyclonal Antibody (MP294014) is a rabbit polyclonal antibody detecting EGFLAM in ELISA, IHC, WB. Suitable for Mouse, Rat.
Highlights
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| 종 반응성 | Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse EGFLAM (Asp40-Thr236). | ||||||||
| 타겟 | Pikachurin (EGF-like, fibronectin type-III and laminin G-like domain-containing protein) (Nectican) | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q4VBE4 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Pikachurin (EGFLAM) is a ~110 kDa protein. Involved in both the retinal photoreceptor ribbon synapse formation and physiological functions of visual perception. Plays a key role in the synaptic organization of photoreceptors by mediating transsynaptic interaction between alpha-dystroglycan and GPR179 on the postsynaptic membrane. Necessary for proper bipolar dendritic tip apposition to the photoreceptor ribbon synapse. Promotes matrix assembly and cell adhesiveness. 1. Sato, S. et al. (2008) Nature neuroscience 11, 923-31. PMID: 18641643 2. Manabe, R. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 12849-54. PMID: 18757743 3. Orlandi, C. et al. (2018) Cell reports 25, 130-145.e5. PMID: 30282023 | ||||||||
| 참고사항 | For research use only. |
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