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| 카탈로그 번호 | MX061014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse FCRN/FCGRT Polyclonal Antibody (MX061014) is a rabbit polyclonal antibody detecting FCRN/FCGRT in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 종 반응성 | Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse FCGRT/FCRN (Arg25-Ser292). | ||||||||
| 타겟 | IgG receptor FcRn large subunit p51 (FcRn) (IgG Fc fragment receptor transporter alpha chain) (Neonatal Fc receptor) | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q61559 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | IgG receptor FcRn large subunit p51 (FCGRT) is a ~40 kDa protein. Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk. IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. 1. Ahouse, JJ. et al. (1993) Journal of immunology (Baltimore, Md. : 1950) 151, 6076-88. PMID: 7504013 | ||||||||
| 참고사항 | For research use only. |
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