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| 카탈로그 번호 | MV664014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse GP6 Polyclonal Antibody (MV664014) is a rabbit polyclonal antibody detecting GP6. Suitable for Mouse.
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| 종 반응성 | Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse GP6 (Ser101-Leu206). | ||||||||
| 타겟 | GP6, GPVI, Glycoprotein 6, Platelet glycoprotein VI | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P0C191 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Platelet glycoprotein VI (GP6) is a ~34 kDa protein. Collagen receptor involved in collagen-induced platelet adhesion and activation. Plays a key role in platelet procoagulant activity and subsequent thrombin and fibrin formation. This procoagulant function may contribute to arterial and venous thrombus formation. The signaling pathway involves the FcR gamma-chain, the Src kinases (likely FYN or LYN) and SYK, the adapter protein LAT and leads to the activation of PLCG2. 1. Lockyer, S. et al. (2006) Thrombosis research 118, 371-80. PMID: 16139873 2. Pokidysheva, E. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 161-6. PMID: 24368846 | ||||||||
| 참고사항 | For research use only |
Western blot analysis was performed using anti-GP6 polyclonal antibody at 1ug/mL on various samples.
Lane 1: SH-SY5Y cell lysate
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