

| 카탈로그 번호 | MV476014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse HDAC9 Polyclonal Antibody (MV476014) is a rabbit polyclonal antibody detecting Hdac9 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse HDAC9 (Val37-Pro161). | ||||||||
| 타겟 | Histone deacetylase 9, HD9, 3.5.1.98, Histone deacetylase 7B, HD7b, Histone deacetylase-related protein, MEF2-interacting transcription repressor MITR, Hdac9, Hdac7b, Hdrp, Mitr | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q99N13 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Histone deacetylase 9 (HDAC9) is a ~65 kDa protein. Devoided of intrinsic deacetylase activity, promotes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) by recruiting HDAC1 and HDAC3. Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Represses MEF2-dependent transcription, inhibits skeletal myogenesis and may be involved in heart development. Protects neurons from apoptosis, both by inhibiting JUN phosphorylation by MAPK10 and by repressing JUN transcription via HDAC1 recruitment to JUN promoter. | ||||||||
| 참고사항 | For research use only. |
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