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| 카탈로그 번호 | MV556014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse IL1RAP Polyclonal Antibody (MV556014) is a rabbit polyclonal antibody detecting Il1rap in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 종 반응성 | Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse IL1RAP (Ser21-Lys350). | ||||||||
| 타겟 | Interleukin-1 receptor accessory protein, IL-1 receptor accessory protein, IL-1RAcP, 3.2.2.6, Interleukin-33 receptot beta chain, Il1rap | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q61730 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Interleukin-1 receptor accessory protein (IL1RAP) is a ~65 kDa protein. Coreceptor for IL1RL2 in the IL-36 signaling system. Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. 1. Yamagata, A. et al. (2015) Nature communications 6, 6926. PMID: 25908590 | ||||||||
| 참고사항 | For research use only. |
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