Anti-Mouse IL-5 Polyclonal Antibody (MY218014)

Name: Anti-Mouse IL-5 Polyclonal Antibody
Brand: abinScience
SKU: MY218014
Price: 168 USD
Availability: InStock

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사양:

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MY218014

설명

Anti-Mouse IL5 Polyclonal Antibody (MY218014) is a rabbit polyclonal antibody detecting Il5. Suitable for Rat and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse IL5 (Met21-Gly133).

타겟

B-cell growth factor II, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, IL-5, Il-5, Il5, Interleukin-5, T-cell replacing factor, TRF

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P04401

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Interleukin-5 (IL5) is a ~15 kDa protein. Homodimeric cytokine expressed predominantly by T-lymphocytes and NK cells that plays an important role in the survival, differentiation, and chemotaxis of eosinophils. Also acts on activated and resting B-cells to induce immunoglobulin production, growth, and differentiation. Mechanistically, exerts its biological effects through a receptor composed of IL5RA subunit and the cytokine receptor common subunit beta/CSF2RB. Binding to the receptor leads to activation of various kinases including LYN, SYK and JAK2 and thereby propagates signals through the RAS-MAPK and JAK-STAT5 pathways respectively. IL5 is the therapeutic target of mepolizumab (Nucala).

1. Vallance, BA. et al. (1999) The American journal of physiology 277, G400-8. PMID: 10444455

2. Barry, SC. et al. (1991) Cytokine 3, 339-44. PMID: 1873482

3. Karasuyama, H. et al. (1988) The Journal of experimental medicine 167, 1377-90. PMID: 3128631

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Mouse IL-5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse IL-5 Polyclonal Antibody (MY218014)

개요

이미지

참고 문헌

데이터시트

SDS

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