

| 카탈로그 번호 | MC068014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse LHFPL5 Polyclonal Antibody (MC068014) is a rabbit polyclonal antibody detecting LHFPL tetraspan subfamily member 5 protein isoform X2; Lhfpl5 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 종 반응성 | Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant mouse LHFPL5 (Ile50-Met98&Asp150-Arg176&Arg202-Val219). | ||||||||
| 타겟 | LHFPL tetraspan subfamily member 5 protein isoform X2; Lhfpl5 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q4KL25 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | LHFPL tetraspan subfamily member 5 protein (LHFPL5) is a ~24 kDa protein. Auxiliary subunit of the mechanotransducer (MET) non-specific cation channel complex located at the tips of the shorter stereocilia of cochlear hair cells and that mediates sensory transduction in the auditory system. The MET complex is composed of two dimeric pore-forming ion-conducting transmembrane TMC (TMC1 or TMC2) subunits, and aided by several auxiliary proteins including LHFPL5, TMIE, CIB2/3 and TOMT, and the tip-link PCDH15. Functionally couples PCDH15 to the transduction channel. 1. Longo-Guess, CM. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 7894-9. PMID: 15905332 2. Xiong, W. et al. (2012) Cell 151, 1283-95. PMID: 23217710 3. Fettiplace, R. et al. (2022) Proceedings of the National Academy of Sciences of the United States of America 119, e2210849119. PMID: 36191207 | ||||||||
| 참고사항 | For research use only |
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