Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998) (MS714107)

Name: Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998)
Brand: abinScience
SKU: MS714107
Price: 191 USD
Availability: InStock

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사양:

50ug
100ug

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

MS714107

종 반응성

Human, Mouse

응용 분야

FCM, WB

숙주 종

Mouse

클론성

Monoclonal

이소타입

IgG2a, kappa

클론 ID

SAA1998

타겟

SCA-2, TSA-1, 9804, Retinoic acid-induced gene E protein, TSA1, Lymphocyte antigen 6E, Ly-6E, Stem cell antigen 2, Thymic shared antigen 1, SCA2, RIGE, LY6E, RIG-E

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

Q64253

형태

Liquid

저장 완충액

0.01M PBS pH 7.4

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

배경

Lymphocyte antigen 6E (LY6E/SCA-2) is a ~14 kDa protein. GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane, leading to CD3Z/CD247 phosphorylation modulation. Restricts the entry of murine coronavirus, mouse hepatitis virus, by interfering with spike protein-mediated membrane fusion. Also plays an essential role in placenta formation by acting as the main receptor for syncytin-A (SynA). Therefore, participates in the normal fusion of syncytiotrophoblast layer I (SynT-I) and in the proper morphogenesis of both fetal and maternal vasculatures within the placenta.

1. Noda, S. et al. (1996) The Journal of experimental medicine 183, 2355-60. PMID: 8642345

2. Kosugi, A. et al. (1998) The Journal of biological chemistry 273, 12301-6. PMID: 9575182

3. Pfaender, S. et al. (2020) Nature microbiology 5, 1330-1339. PMID: 32704094

4. Bacquin, A. et al. (2017) Journal of virology 91. PMID: 28679758

5. Langford, MB. et al. (2018) Scientific reports 8, 3961. PMID: 29500366

6. Wu, M. et al. (2015) The Journal of biological chemistry 290, 24509-18. PMID: 26276394

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-LY6E/SCA-2 monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 50ng
Lane 2: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 30ng
Lane 3: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 20ng
Lane 4: recombinant human LY6E/SCA-2 (Catalog No: HS714011), 10ng
SDS-PAGE

SDS-PAGE for Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998)

참고 문헌

데이터시트

Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse LY6E/SCA-2 Recombinant Antibody (SAA1998) (MS714107)

개요

이미지

참고 문헌

데이터시트

SDS

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