Anti-Mouse MDK/Midkine Polyclonal Antibody (MB964014)

Name: Anti-Mouse MDK/Midkine Polyclonal Antibody
Brand: abinScience
SKU: MB964014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MB964014

설명

Anti-Mouse MDK/Midkine Polyclonal Antibody (MB964014) is a rabbit polyclonal antibody detecting Midkine. Suitable for Mouse and Rat.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse MDK/Midkine (Lys23-Asp140).

타겟

MK, Mdk, Midkine, Mk, Retanoic acid-responsive protein, Retinoic acid-induced differentiation factor

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P12025

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Midkine (MDK) is a ~15 kDa protein. Secreted protein that functions as a cytokine and growth factor and mediates its signal through cell-surface proteoglycan and non-proteoglycan receptors. Binds cell-surface proteoglycan receptors via their chondroitin sulfate (CS) groups. Thereby regulates many processes like inflammatory response, cell proliferation, cell adhesion, cell growth, cell survival, tissue regeneration, cell differentiation and cell migration. Participates in inflammatory processes by exerting two different activities. Firstly, mediates neutrophils and macrophages recruitment to the sites of inflammation both by direct action by cooperating namely with ITGB2 via LRP1 and by inducing chemokine expression.

1. Ichihara-Tanaka, K. et al. (2006) The Journal of biological chemistry 281, 30857-64. PMID: 16901907

2. Zou, P. et al. (2006) Journal of neurochemistry 99, 1470-9. PMID: 17230638

3. Horiba, M. et al. (2000) The Journal of clinical investigation 105, 489-95. PMID: 10683378

4. Ochiai, K. et al. (2004) Liver international : official journal of the International Association for the Study of the Liver 24, 484-91. PMID: 15482347

5. Kawai, H. et al. (2004) The American journal of pathology 165, 1603-12. PMID: 15509530

6. Horiba, M. et al. (2006) Circulation 114, 1713-20. PMID: 17015789

7. Takenaka, H. et al. (2009) American journal of physiology. Heart and circulatory physiology 296, H462-9. PMID: 19060126

8. Weckbach, LT. et al. (2014) Blood 123, 1887-96. PMID: 24458438

9. Haffner-Luntzer, M. et al. (2014) PloS one 9, e116282. PMID: 25551381

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Mouse MDK/Midkine Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse MDK/Midkine Polyclonal Antibody (MB964014)

개요

이미지

참고 문헌

데이터시트

SDS

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