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| 카탈로그 번호 | MV463014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse NCOA3 Polyclonal Antibody (MV463014) is a rabbit polyclonal antibody detecting Ncoa3. Suitable for Rat and Mouse.
Highlights
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| 종 반응성 | Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse NCOA3 (Asp112-Arg375). | ||||||||
| 타겟 | ACTR, AIB-1, Aib1, Amplified in breast cancer-1 protein homolog, CBP-interacting protein, EC:2.3.1.48, NCoA-3, Ncoa3, Nuclear receptor coactivator 3, Pcip, RAC-3, Rac3, Receptor-associated coactivator 3, SRC-3, Steroid receptor coactivator protein 3, TRAM-1, Thyroid hormone receptor activator molecule 1, Tram1, p/CIP, pCIP | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O09000 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 배경 | Nuclear receptor coactivator 3 (NCOA3) is a ~151 kDa protein. Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, probably via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit. | ||||||||
| 참고사항 | For research use only |
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