Anti-Mouse OAZ1 Polyclonal Antibody (MX222014)

Name: Anti-Mouse OAZ1 Polyclonal Antibody
Brand: abinScience
SKU: MX222014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

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사양:

50ug
100ug

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호

MX222014

설명

Anti-Mouse OAZ1 Polyclonal Antibody (MX222014) is a rabbit polyclonal antibody detecting OAZ1. Suitable for Rat and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse OAZ1 (Ser91-Asp227).

타겟

AZ1, OAZ, OAZ1, ODC-Az, Ornithine decarboxylase antizyme 1

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P54369

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Ornithine decarboxylase antizyme 1 (OAZ1) is a ~25 kDa protein. Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome. Triggers ODC degradation by inducing the exposure of a cryptic proteasome-interacting surface of ODC. Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter.

1. López-Contreras, AJ. et al. (2006) The Journal of biological chemistry 281, 30896-906. PMID: 16916800

2. López-Contreras, AJ. et al. (2008) The Journal of biological chemistry 283, 20761-9. PMID: 18508777

3. Snapir, Z. et al. (2008) The Biochemical journal 410, 613-9. PMID: 18062773

4. López-Contreras, AJ. et al. (2009) Journal of cellular biochemistry 107, 732-40. PMID: 19449338

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Mouse OAZ1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse OAZ1 Polyclonal Antibody (MX222014)

개요

이미지

참고 문헌

데이터시트

SDS