

| 카탈로그 번호 | MA272014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse PLXNB3 Polyclonal Antibody (MA272014) is a rabbit polyclonal antibody detecting PLXNB3 in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 종 반응성 | Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse PLXNB3 (Cys464-Asp609). | ||||||||
| 타겟 | PLXNB3, Plexin-B3, PLXN6, KIAA1206 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9QY40 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Plexin-B3 (PLXNB3) is a ~208 kDa protein. Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca(2+)/Mg(2+)-dependent cell aggregation. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1. Seem to be non-essential for normal development and function of the central nervous system. | ||||||||
| 참고사항 | For research use only. |
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