Anti-Mouse S100A9 Polyclonal Antibody (MY562014)

Name: Anti-Mouse S100A9 Polyclonal Antibody
Brand: abinScience
SKU: MY562014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

MY562014

설명

Anti-Mouse S100A9 Polyclonal Antibody (MY562014) is a rabbit polyclonal antibody detecting S100a9 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse S100A9 (Ala2-Lys113).

타겟

Protein S100-A9, Calgranulin-B, Leukocyte L1 complex heavy chain, Migration inhibitory factor-related protein 14, MRP-14, p14, S100 calcium-binding protein A9, S100a9, Cagb, Mrp14

정제

Purified by antigen affinity column.

등록번호

P31725

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Protein S100-A9 (S100A9) is a ~13 kDa protein. S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. Also participates in regulatory T-cell differentiation together with CD69.

1. Vogl, T. et al. (2004) Blood 104, 4260-8. PMID: 15331440

2. Vogl, T. et al. (2007) Nature medicine 13, 1042-9. PMID: 17767165

3. Boyd, JH. et al. (2008) Circulation research 102, 1239-46. PMID: 18403730

4. Björk, P. et al. (2009) PLoS biology 7, e97. PMID: 19402754

5. Riva, M. et al. (2012) Immunology 137, 172-82. PMID: 22804476

6. Daitoku, H. et al. (2021) The Journal of biological chemistry 297, 101230. PMID: 34562450

7. Averill, MM. et al. (2011) Circulation 123, 1216-26. PMID: 21382888

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-S100A9 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse spleen lysate
Lane 2: Rat spleen lysate

참고 문헌

데이터시트

Anti-Mouse S100A9 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse S100A9 Polyclonal Antibody (MY562014)

개요

이미지

참고 문헌

데이터시트

SDS

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