Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014)

Name: Anti-Mouse Serpinb1a Polyclonal Antibody
Brand: abinScience
SKU: MD634014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MD634014

설명

Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014) is a rabbit polyclonal antibody detecting Serpinb1a. Suitable for Rat and Mouse.

Highlights

●Multi-Species — Cross-reactive for translational research.

종 반응성

Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse Serpinb1a (Met1-Pro379).

타겟

Leukocyte elastase inhibitor A, Serine protease inhibitor EIA, Serpin B1a, Serpinb1, Serpinb1a

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q9D154

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

배경

Leukocyte elastase inhibitor A (Serpinb1a) is a ~42 kDa protein. Neutrophil serine protease inhibitor that plays an essential role in the regulation of the innate immune response, inflammation and cellular homeostasis. Acts primarily to protect the cell from proteases released in the cytoplasm during stress or infection. These proteases are important in killing microbes but when released from granules, these potent enzymes also destroy host proteins and contribute to mortality. Regulates the activity of the neutrophil proteases elastase, cathepsin G, proteinase-3, chymase, chymotrypsin, and kallikrein-3. Also acts as a potent intracellular inhibitor of granzyme H.

1. Benarafa, C. et al. (2007) The Journal of experimental medicine 204, 1901-9. PMID: 17664292

2. Benarafa, C. et al. (2011) Journal of leukocyte biology 90, 21-9. PMID: 21248149

3. Benarafa, C. (2011) Methods in enzymology 499, 135-48. PMID: 21683252

4. Choi, YJ. et al. (2019) Nature immunology 20, 276-287. PMID: 30692621

5. Benarafa, C. et al. (2002) The Journal of biological chemistry 277, 42028-33. PMID: 12189154

6. El Ouaamari, A. et al. (2016) Cell metabolism 23, 194-205. PMID: 26701651

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Mouse Serpinb1a Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse Serpinb1a Polyclonal Antibody (MD634014)

개요

이미지

참고 문헌

데이터시트

SDS