

| 카탈로그 번호 | MA149014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Mouse Timd2/G9D3 protein Polyclonal Antibody (MA149014) is a rabbit polyclonal antibody detecting Timd2/G9D3 protein in ELISA, IHC, WB. Suitable for Mouse.
Highlights
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| 종 반응성 | Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Mouse Timd2/G9D3 protein (Ser21-Glu129). | ||||||||
| 타겟 | T cell immunoglobulin and mucin domain containing 2, Timd2, G9D3 protein | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q8R183 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | T-cell immunoglobulin and mucin domain-containing protein 2 (Timd2/G9D3 protein) is a ~33 kDa protein. Cell surface glycoprotein that participates in iron homeostasis in the liver, the kidney, the retina and oligodendrocytes by acting as a receptor of H-ferritin. Mechanistically, mediates iron-containing ferritin uptake via an endocytic pathway, trafficking to endosomes and subsequently to lysosomes. Plays also an important role in the regulation of Th2 immunity. Receptor for SEMA4A involved in the regulation of T-cell function, enhancing T-cell activation. 1. Chen, TT. et al. (2005) The Journal of experimental medicine 202, 955-65. PMID: 16203866 2. Valença, A. et al. (2021) Experimental eye research 202, 108292. PMID: 33065090 3. Chakravarti, S. et al. (2005) The Journal of experimental medicine 202, 437-44. PMID: 16043519 4. Han, J. et al. (2011) PloS one 6, e23800. PMID: 21886823 5. Kumanogoh, A. et al. (2002) Nature 419, 629-33. PMID: 12374982 | ||||||||
| 참고사항 | For research use only. |
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