Anti-Mouse GITR/TNFRSF18 Polyclonal Antibody (MP087014)

Name: Anti-Mouse GITR/TNFRSF18 Polyclonal Antibody
Brand: abinScience
SKU: MP087014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MP087014

설명

Anti-Mouse GITR/TNFRSF18 Polyclonal Antibody (MP087014) is a rabbit polyclonal antibody detecting GITR/TNFRSF18 in ELISA, IHC, WB. Suitable for Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse TNFSF18 (Glu50-Ser173).

타겟

Tumor necrosis factor ligand superfamily member 18 (GITR ligand) (GITRL) (Glucocorticoid-induced TNF-related ligand)

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

Q7TS55

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Tumor necrosis factor ligand superfamily member 18 (TNFSF18/GITRL) is a ~19 kDa protein. Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.

1. Yu, KY. et al. (2003) Biochemical and biophysical research communications 310, 433-8. PMID: 14521928

2. Kim, JD. et al. (2003) Genes and immunity 4, 564-9. PMID: 14647196

3. Tone, M. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 15059-64. PMID: 14608036

4. Ji, HB. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 172, 5823-7. PMID: 15128759

5. Zhou, Z. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 641-5. PMID: 18178614

6. Lacal, PM. et al. (2013) The Journal of pharmacology and experimental therapeutics 347, 164-72. PMID: 23892569

7. Liao, G. et al. (2014) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 28, 474-84. PMID: 24107315

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Mouse GITR/TNFRSF18 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse GITR/TNFRSF18 Polyclonal Antibody (MP087014)

개요

이미지

참고 문헌

데이터시트

SDS