Anti-Mouse VLDLR Polyclonal Antibody (MX210014)

Name: Anti-Mouse VLDLR Polyclonal Antibody
Brand: abinScience
SKU: MX210014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

MX210014

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Mouse VLDLR (Glu440-Asn684).

타겟

Very low-density lipoprotein receptor (VLDL receptor) (VLDL-R)

정제

Purified by antigen affinity column.

등록번호

P98156

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Very low-density lipoprotein receptor (VLDLR) is a ~96 kDa protein. Multifunctional cell surface receptor that binds VLDL and transports it into cells by endocytosis and therefore plays an important role in energy metabolism. Also binds to a wide range of other molecules including Reelin/RELN or apolipoprotein E/APOE-containing ligands as well as clusterin/CLU. In the off-state of the pathway LRP8 and VLDLR form homo or heterooligomers. Upon binding to ligands, homooligomers are rearranged to higher order receptor clusters that transmit the extracellular RELN signal to intracellular signaling processes by binding to DAB1 on its cytoplasmic tail. This interaction results in phosphorylation of DAB1 leading to the ultimate cell responses required for the correct positioning of newly generated neurons.

1. Tacken, PJ. et al. (2000) Journal of lipid research 41, 2055-62. PMID: 11108739

2. Nguyen, A. et al. (2014) The Journal of biological chemistry 289, 1688-703. PMID: 24293365

3. Fuchigami, T. et al. (2013) Genes to cells : devoted to molecular & cellular mechanisms 18, 410-24. PMID: 23506116

4. Hack, I. et al. (2007) Development (Cambridge, England) 134, 3883-91. PMID: 17913789

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-Mouse VLDLR Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse VLDLR Polyclonal Antibody (MX210014)

개요

이미지

참고 문헌

데이터시트

SDS

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