Anti-MPP5 Polyclonal Antibody (HV348014)

Name: Anti-MPP5 Polyclonal Antibody
Brand: abinScience
SKU: HV348014
Price: 96 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HV348014

설명

Anti-MPP5 Polyclonal Antibody (HV348014) is a rabbit polyclonal antibody detecting MPP5 in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, Rat, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human MPP5 (Asn455-Arg675).

타겟

PALS1, MAGUK p55 subfamily member 5, MPP5

정제

Purified by antigen affinity column.

등록번호

Q8N3R9

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Protein PALS1 (MPP5) is a ~77 kDa protein. Plays a role in tight junction biogenesis and in the establishment of cell polarity in epithelial cells. Also involved in adherens junction biogenesis by ensuring correct localization of the exocyst complex protein EXOC4/SEC8 which allows trafficking of adherens junction structural component CDH1 to the cell surface. Plays a role through its interaction with CDH5 in vascular lumen formation and endothelial membrane polarity. Required during embryonic and postnatal retinal development. Required for the maintenance of cerebellar progenitor cells in an undifferentiated proliferative state, preventing premature differentiation, and is required for cerebellar histogenesis, fissure formation, cerebellar layer organization and cortical development.

1. Wells, CD. et al. (2006) Cell 125, 535-48. PMID: 16678097

2. Li, Y. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 17444-9. PMID: 25385611

3. Brinkmann, BF. et al. (2016) Molecular biology of the cell 27, 2811-21. PMID: 27466317

4. Carvalho, G. et al. (2011) PloS one 6, e18159. PMID: 21479189

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-MPP5 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-MPP5 Polyclonal Antibody (HV348014)

개요

이미지

참고 문헌

데이터시트

SDS

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