

| 카탈로그 번호 | VK094034 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-MRV-3 Outer capsid protein mu-1 Polyclonal Antibody (VK094034) is a rabbit polyclonal antibody detecting MRV-3 Outer capsid protein mu-1 in ELISA, IHC, WB. Suitable for Reovirus type 1, Reovirus type 2, and Reovirus type 3.
Highlights
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| 종 반응성 | Mammalian orthoreovirus 1 (MRV1) | ||||
| 응용 분야 | ELISA, IHC, WB | ||||
| 숙주 종 | Rabbit | ||||
| 클론성 | Polyclonal | ||||
| 이소타입 | IgG | ||||
| 면역원 | E. coli - derived recombinant MRV-3 Outer capsid protein mu-1 (Lys317-Ser500). | ||||
| 타겟 | M2 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Purified by antigen affinity column. | ||||
| 등록번호 | P11077, P11078, P12397 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Outer capsid protein mu-1 is a ~76 kDa protein. Major outer capsid protein involved in host cell membrane penetration. In the endocytic compartment, outer-capsid protein sigma-3 is removed by cathepsin proteases, which exposes the viral membrane-penetration protein mu-1. Both myristoylated peptides mu-1N and phi are released during infectious subvirion particles (ISVP) formation in the endosome. They associate with host membranes and mu-1N induces permeabilization and delivery of transcriptionally active viral particles into the host cell cytoplasm. Seems to induce apoptosis in the host cell. | ||||
| 참고사항 | For research use only |
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