Anti-MRV-3 Sigma3/S4 Polyclonal Antibody (VK094024)

Name: Anti-MRV-3 Sigma3/S4 Polyclonal Antibody
Brand: abinScience
SKU: VK094024
Price: 168 USD
Availability: InStock

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사양:

50ug
100ug

수량:

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

VK094024

설명

Anti-MRV-3 Sigma3/S4 Polyclonal Antibody (VK094024) is a rabbit polyclonal antibody detecting MRV-3 Sigma3/S4 in ELISA, IHC, WB. Suitable for Reovirus type 1, Reovirus type 2, and Reovirus type 3.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Mammalian orthoreovirus 1 (MRV1)

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant MRV-3 Sigma3/S4 (Met1-Gly365).

타겟

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

P30211, P07939, P03527

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000,IHC:1:50-1:500,WB:1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Outer capsid protein sigma-3 (Sigma3/S4) is a ~41 kDa protein. Outer layer capsid protein that stimulates translation by blocking the activation of the dsRNA-dependent protein kinase EIF2AK2/PKR, thereby inhibiting the host interferon response. Sigma3 prevents the activation of EIF2AK2 by competing with the kinase for dsRNA-binding. During virus assembly, the inner layer proteins lambda-1 and the turret protein lambda-2 form the star core, followed by the stepwise attachment of sigma-2 that completes the core and mu1/sigma3 that complete the outer layer. Binds to the host neuronal receptor RTN4R for viral entry into host neural cells.

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-MRV-3 Sigma3/S4 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-MRV-3 Sigma3/S4 Polyclonal Antibody (VK094024)

개요

이미지

참고 문헌

데이터시트

SDS