

| 카탈로그 번호 | VK094014 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-MRV-3 SigmaNS/S3 Polyclonal Antibody (VK094014) is a rabbit polyclonal antibody detecting MRV-3 SigmaNS/S3 in ELISA, IHC, WB. Suitable for Reovirus type 2, Reovirus type 1, and Reovirus type 3.
Highlights
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| 종 반응성 | Mammalian orthoreovirus 1 (MRV1) | ||||
| 응용 분야 | ELISA, IHC, WB | ||||
| 숙주 종 | Rabbit | ||||
| 클론성 | Polyclonal | ||||
| 이소타입 | IgG | ||||
| 면역원 | E. coli - derived recombinant MRV-3 SigmaNS/S3 (Met1-Val366). | ||||
| 타겟 | sigma-NS protein, S3 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Purified by antigen affinity column. | ||||
| 등록번호 | P07940, P12002, P03526 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Protein sigma-NS (SigmaNS/S3) is a ~41 kDa protein. Protein that binds to ssRNA and participates with protein mu-NS in forming the matrix of viral factories, which are large inclusions in the host cytoplasm where replication intermediates are assembled and viral RNA replication takes place. Plays a role in the inhibition of the integrated stress response (ISR) to escape from host cell translational shutoff. Participates in the disruption of stress granules (SG) through its association with host G3BP1 and mu-NS. 1. Gillian, AL. et al. (1998) Virology 240, 1-11. PMID: 9448684 2. Choudhury, P. et al. (2017) Journal of virology 91. PMID: 28794026 | ||||
| 참고사항 | For research use only |
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