Anti-MTA1 Polyclonal Antibody (HA784014)

Name: Anti-MTA1 Polyclonal Antibody
Brand: abinScience
SKU: HA784014
Price: 168 USD
Availability: InStock

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100ug

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개요
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개요

카탈로그 번호

HA784014

설명

Anti-MTA1 Polyclonal Antibody (HA784014) is a rabbit polyclonal antibody detecting Metastasis-associated protein MTA1; MTA1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human MTA1 (Met1-Leu430).

타겟

Metastasis-associated protein MTA1; MTA1

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q13330, Q8K4B0, Q62599

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Metastasis-associated protein MTA1 is a ~80 kDa protein. Transcriptional coregulator which can act as both a transcriptional corepressor and coactivator. Acts as a component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin. In the NuRD complex, regulates transcription of its targets by modifying the acetylation status of the target chromatin and cofactor accessibility to the target DNA. In conjunction with other components of NuRD, acts as a transcriptional corepressor of BRCA1, ESR1, TFF1 and CDKN1A. Acts as a transcriptional coactivator of BCAS3, and SUMO2, independent of the NuRD complex.

1. Gururaj, AE. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 6670-5. PMID: 16617102

2. Balasenthil, S. et al. (2007) Cancer research 67, 7132-8. PMID: 17671180

3. Molli, PR. et al. (2008) Oncogene 27, 1971-80. PMID: 17922032

4. Cong, L. et al. (2011) The Journal of biological chemistry 286, 43793-43808. PMID: 21965678

5. Kang, HJ. et al. (2014) Cancer research 74, 1484-94. PMID: 24413532

6. Le Guezennec, X. et al. (2006) Molecular and cellular biology 26, 843-51. PMID: 16428440

7. Hoffmeister, H. et al. (2017) Nucleic acids research 45, 10534-10554. PMID: 28977666

8. Li, DQ. et al. (2009) The Journal of biological chemistry 284, 34545-52. PMID: 19837670

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-MTA1 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-MTA1 Polyclonal Antibody (HA784014)

개요

이미지

참고 문헌

데이터시트

SDS