

| 카탈로그 번호 | HT196014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-NARS1 Polyclonal Antibody (HT196014) is a rabbit polyclonal antibody detecting NARS1 in ELISA, IHC, WB. Suitable for Human, Mouse.
Highlights
|
||||||||
| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human NARS1 (Met1-Arg330). | ||||||||
| 타겟 | Asparagine--tRNA ligase, cytoplasmic, NARS, NRS, Asparaginyl-tRNA synthetase, NARS1, Asparaginyl-tRNA synthetase 1, AsnRS | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O43776 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||||||
| 제품 사용 정보 |
| ||||||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Asparagine--tRNA ligase, cytoplasmic (NARS1) is a ~62 kDa protein. Catalyzes the attachment of asparagine to tRNA(Asn) in a two-step reaction: asparagine is first activated by ATP to form Asn-AMP and then transferred to the acceptor end of tRNA(Asn). In addition to its essential role in protein synthesis, acts as a signaling molecule that induced migration of CCR3-expressing cells. Has an essential role in the development of the cerebral cortex, being required for proper proliferation of radial glial cells. 1. Manole, A. et al. (2020) American journal of human genetics 107, 311-324. PMID: 32738225 2. Wang, L. et al. (2020) Nature communications 11, 4038. PMID: 32788587 3. Beaulande, M. et al. (1998) Nucleic acids research 26, 521-4. PMID: 9421509 4. Howard, OM. et al. (2002) The Journal of experimental medicine 196, 781-91. PMID: 12235211 5. Park, JS. et al. (2018) International journal of biological macromolecules 120, 835-845. PMID: 30171954 | ||||||||
| 참고사항 | For research use only. |

Lane 1: HepG2 cell lysate
Lane 2: K562 cell lysate
Lane 3: Hela cell lysate
Lane 4: RAW264.7 cell lysate
Lane 5: 293T cell lysate
Lane 6: LO2 cell lysate
Lane 7: Jurkat cell lysate


빠른 접근
문의하기
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206

中文
English
한국어
日本語
Español
Français
Русский