Anti-NCSTN Polyclonal Antibody (HV481014)

Name: Anti-NCSTN Polyclonal Antibody
Brand: abinScience
SKU: HV481014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD): --

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HV481014

설명

Anti-NCSTN Polyclonal Antibody (HV481014) is a rabbit polyclonal antibody detecting NCSTN in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human NCSTN (Gln420-Asp655).

타겟

KIAA0253, Nicastrin, NCSTN

정제

Purified by antigen affinity column.

등록번호

Q92542

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Nicastrin (NCSTN) is a ~78 kDa protein. Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.

1. Yu, G. et al. (2000) Nature 407, 48-54. PMID: 10993067

2. Edbauer, D. et al. (2003) Nature cell biology 5, 486-8. PMID: 12679784

3. Lu, P. et al. (2014) Nature 512, 166-170. PMID: 25043039

4. Bai, XC. et al. (2015) Nature 525, 212-217. PMID: 26280335

5. Yang, G. et al. (2019) Nature 565, 192-197. PMID: 30598546

6. Zhou, R. et al. (2019) Science (New York, N.Y.) 363. PMID: 30630874

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-NCSTN Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-NCSTN Polyclonal Antibody (HV481014)

개요

이미지

참고 문헌

데이터시트

SDS