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| 카탈로그 번호 | JN971013 | ||||||
|---|---|---|---|---|---|---|---|
| 종 반응성 | Neisseria meningitidis | ||||||
| 응용 분야 | DB, ELISA, WB | ||||||
| 숙주 종 | Human | ||||||
| 클론성 | Monoclonal | ||||||
| 이소타입 | VHH-hFc | ||||||
| 클론 ID | G9 | ||||||
| 타겟 | nadA, Neisseria adhesin A | ||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||||
| 등록번호 | Q9JXK7 | ||||||
| RRID | Anti-Neisseria meningitidis NadA/Neisseria adhesin A Antibody (G9) (abinScience Cat# JN971013, RRID:AB_3727795) |
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| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 배경 | Neisseria adhesin A (NadA) is a ~37 kDa protein. Adheres to and induces bacterial uptake by human epithelial cells (Probable). Upon expression in engineered Y.enterocolitica confers an 11- to 15-fold increase in bacterial adherence and uptake by human epithelial cell lines; part of the uptake is mediated by integrin beta-1 (ITGB1) suggesting it may be a human receptor for NadA. A bacterial cell surface protein; antisera against this protein induce complement-mediated killing of this and other strains. 1. Nägele, V. et al. (2011) The Journal of biological chemistry 286, 20536-46. PMID: 21471204 2. Comanducci, M. et al. (2002) The Journal of experimental medicine 195, 1445-54. PMID: 12045242 | ||||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Neisseria meningitidis NadA/Neisseria adhesin A Antibody (G9)
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
