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| 카탈로그 번호 | HX253014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-NFKB2 Polyclonal Antibody (HX253014) is a rabbit polyclonal antibody detecting NFKB2 in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human NFKB2 (Pro38-Leu343). | ||||||||
| 타겟 | Lymphocyte translocation chromosome 10 protein, NFKB2, LYT10, H2TF1, Nuclear factor NF-kappa-B p100 subunit, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, DNA-binding factor KBF2, Oncogene Lyt-10, Lyt10 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q00653 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Nuclear factor NF-kappa-B p100 subunit (NFKB2) is a ~96 kDa protein. NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-NFKB2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: THP-1 cell lysate
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