Anti-NPS Polyclonal Antibody (HY501014)

Name: Anti-NPS Polyclonal Antibody
Brand: abinScience
SKU: HY501014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HY501014

설명

Anti-NPS Polyclonal Antibody (HY501014) is a rabbit polyclonal antibody detecting NPS in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human NPS (Ser29-Lys88).

타겟

NPS, Neuropeptide S

정제

Purified by antigen affinity column.

등록번호

P0C0P6

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Neuropeptide S (NPS) is a ~10 kDa protein. Ligand for NPSR1. Binds to its receptor with nanomolar affinity and initiates a G(q)/GNAQ-dependent phospholipase C-activating signaling pathway. This results in Ca(2+) mobilization from intracellular stores and increased intracellular Ca(2+) levels. In addition to this pathway, NPS binding to its receptor activates cAMP/PKA signal transduction. Finally, both pathways converge to activate ERK1/ERK2 phosphorylation and signaling cascade.

1. Xu, YL. et al. (2004) Neuron 43, 487-97. PMID: 15312648

2. Vendelin, J. et al. (2005) American journal of respiratory cell and molecular biology 33, 262-70. PMID: 15947423

3. Roth, AL. et al. (2006) The Journal of biological chemistry 281, 20809-20816. PMID: 16720571

4. Bernier, V. et al. (2006) The Journal of biological chemistry 281, 24704-12. PMID: 16790440

5. Erdmann, F. et al. (2015) PloS one 10, e0117319. PMID: 25714705

6. Liao, Y. et al. (2016) The Journal of biological chemistry 291, 7505-16. PMID: 26865629

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-NPS Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-NPS Polyclonal Antibody (HY501014)

개요

이미지

참고 문헌

데이터시트

SDS