

| 카탈로그 번호 | HW375014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-NR2C2 Polyclonal Antibody (HW375014) is a rabbit polyclonal antibody detecting NR2C2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human NR2C2 (Arg191-Pro503). | ||||||||
| 타겟 | Orphan nuclear receptor TAK1, Orphan nuclear receptor TR4, TAK1, Nuclear receptor subfamily 2 group C member 2, TR4, NR2C2, Testicular receptor 4 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P49116 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Nuclear receptor subfamily 2 group C member 2 (NR2C2) is a ~65 kDa protein. Orphan nuclear receptor that can act as a repressor or activator of transcription. An important repressor of nuclear receptor signaling pathways such as retinoic acid receptor, retinoid X, vitamin D3 receptor, thyroid hormone receptor and estrogen receptor pathways. May regulate gene expression during the late phase of spermatogenesis. Together with NR2C1, forms the core of the DRED (direct repeat erythroid-definitive) complex that represses embryonic and fetal globin transcription including that of GATA1. Binds to hormone response elements (HREs) consisting of two 5'-AGGTCA-3' half site direct repeat consensus sequences. | ||||||||
| 참고사항 | For research use only. |
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