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| 카탈로그 번호 | HB306014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-NTMT2 Polyclonal Antibody (HB306014) is a rabbit polyclonal antibody detecting N-terminal Xaa-Pro-Lys N-methyltransferase 2; 2.1.1.299; Alpha N-terminal protein methyltransferase 1B; Methyltransferase-like protein 11B; X-Pro-Lys N-terminal protein methyltransferase 1B; NTM1B; NTMT2; C1orf184; METTL11B; NRMT2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant human NTMT2 (Met1-Ser283). | ||||||||
| 타겟 | N-terminal Xaa-Pro-Lys N-methyltransferase 2; 2.1.1.299; Alpha N-terminal protein methyltransferase 1B; Methyltransferase-like protein 11B; X-Pro-Lys N-terminal protein methyltransferase 1B; NTM1B; NTMT2; C1orf184; METTL11B; NRMT2 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q5VVY1, B2RXM4, D3ZVR1 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | N-terminal Xaa-Pro-Lys N-methyltransferase 2 (NTMT2) is a ~32 kDa protein. Alpha N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes monomethylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and Pro in the Pro-Pro-Lys motif. Predominantly functions as a mono-methyltransferase but is also able to di-/tri-methylate the GPKRIA peptide and di-methylate the PPKRIA peptide (in vitro). May activate NTMT1 by priming its substrates for trimethylation. 1. Petkowski, JJ. et al. (2013) The Biochemical journal 456, 453-62. PMID: 24090352 2. Dong, C. et al. (2018) Communications biology 1, 183. PMID: 30417120 | ||||||||
| 참고사항 | For research use only |
Western blot analysis was performed using anti-NTMT2 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse heart lysate
Lane 2: Rat heart lysate
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