

| 카탈로그 번호 | HV971014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-NUMBL Polyclonal Antibody (HV971014) is a rabbit polyclonal antibody detecting NUMBL in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human NUMBL (Ala60-Lys204). | ||||||||
| 타겟 | Numb-R, Numb-like protein, NUMBL, Numb-related protein | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9Y6R0 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Numb-like protein (NUMBL) is a ~64 kDa protein. Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. | ||||||||
| 참고사항 | For research use only. |
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