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| 카탈로그 번호 | HW461014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-NUP62 Polyclonal Antibody (HW461014) is a rabbit polyclonal antibody detecting NUP62 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human NUP62 (Ala186-Lys432). | ||||||||
| 타겟 | Nuclear pore glycoprotein p62, Nucleoporin Nup62, 62 kDa nucleoporin, NUP62 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P37198 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Nuclear pore glycoprotein p62 (NUP62) is a ~53 kDa protein. Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown. 1. Carmo-Fonseca, M. et al. (1991) European journal of cell biology 55, 17-30. PMID: 1915414 2. Hashizume, C. et al. (2013) Cell cycle (Georgetown, Tex.) 12, 3804-16. PMID: 24107630 | ||||||||
| 참고사항 | For research use only. |
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