Anti-OAZ1 Polyclonal Antibody (HX222014)

Name: Anti-OAZ1 Polyclonal Antibody
Brand: abinScience
SKU: HX222014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HX222014

설명

Anti-OAZ1 Polyclonal Antibody (HX222014) is a rabbit polyclonal antibody detecting OAZ1 in ELISA, IHC, WB. Suitable for Bovine, Chicken, and Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human OAZ1 (Phe95-Glu219).

타겟

OAZ1, OAZ, AZ1, Ornithine decarboxylase antizyme 1, ODC-Az

정제

Purified by antigen affinity column.

등록번호

P54368

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ornithine decarboxylase antizyme 1 (OAZ1) is a ~25 kDa protein. Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimer, and targets the monomers for ubiquitin-independent proteolytic destruction by the 26S proteasome. Triggers ODC degradation by inducing the exposure of a cryptic proteasome-interacting surface of ODC. Stabilizes AZIN2 by interfering with its ubiquitination. Also inhibits cellular uptake of polyamines by inactivating the polyamine uptake transporter.

1. Kanerva, K. et al. (2008) The Biochemical journal 409, 187-92. PMID: 17900240

2. Wu, HY. et al. (2015) Proceedings of the National Academy of Sciences of the United States of America 112, 11229-34. PMID: 26305948

3. Wu, D. et al. (2015) Scientific reports 5, 14738. PMID: 26443277

4. Lin, Y. et al. (2002) BMC cell biology 3, 15. PMID: 12097147

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-OAZ1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-OAZ1 Polyclonal Antibody (HX222014)

개요

이미지

참고 문헌

데이터시트

SDS