

| 카탈로그 번호 | VK070014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 브랜드 | abinScience | ||||||||
| 설명 |
Anti-OPG199 Polyclonal Antibody (VK070014) is a rabbit polyclonal antibody detecting OPG199 in ELISA, IHC, WB. Suitable for Variola virus, Cowpox virus, Rabbitpox virus, Monkeypox virus, and Vaccinia virus.
Highlights
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| 종 반응성 | Variola virus, Cowpox virus, Rabbitpox virus, Monkeypox virus, Vaccinia virus | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant cpxv OPG199 (Met1-Leu300). | ||||||||
| 타겟 | CrmA or CPXV207 protein, CrmA | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P07385, A0A7H0DNF9, P42926, P0DSW4, P20842, P15059, P0DSW3, P20841 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Serine proteinase inhibitor 2 (OPG199) is a ~38 kDa protein. Viral serpin that inhibits both cysteine and serine proteinases involved in the regulation of host inflammatory and apoptosis processes. Major anti-apoptotic protein which inhibits both intrinsic and extrinsic pathways and strongly cleaves host CASP1 and CASP8 but is a rather poor inhibitor of host CASP3. Prevents the proteolytic activity of host interleukin-1-beta converting enzyme (ICE) and ICE-like enzymes. Can also block apoptosis through host tumor necrosis factor (TNF) receptor. 1. Simonovic, M. et al. (2000) Protein science : a publication of the Protein Society 9, 1423-7. PMID: 10975564 2. Renatus, M. et al. (2000) Structure (London, England : 1993) 8, 789-97. PMID: 10903953 | ||||||||
| 참고사항 | For research use only |
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