

| 카탈로그 번호 | HA725014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-OTOF Polyclonal Antibody (HA725014) is a rabbit polyclonal antibody detecting Otoferlin; Fer-1-like protein 2; OTOF; FER1L2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Zebrafish.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant human OTOF (Met244-Ala596). | ||||||||
| 타겟 | Otoferlin; Fer-1-like protein 2; OTOF; FER1L2 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9HC10, Q9ESF1, Q9ERC5, Q5SPC5 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Otoferlin is a ~226 kDa protein. Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion and in the control of neurotransmitter release at these output synapses. Interacts in a calcium-dependent manner to the presynaptic SNARE proteins at ribbon synapses of cochlear inner hair cells (IHCs) to trigger exocytosis of neurotransmitter. Also essential to synaptic exocytosis in immature outer hair cells (OHCs). May also play a role within the recycling of endosomes. | ||||||||
| 참고사항 | For research use only |
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