

| 카탈로그 번호 | HA787014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-P2RX1 Polyclonal Antibody (HA787014) is a rabbit polyclonal antibody detecting P2X purinoceptor 1; P2X1; ATP receptor; Purinergic receptor; P2RX1; P2X1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant human P2RX1 (Gln56-Asp327). | ||||||||
| 타겟 | P2X purinoceptor 1; P2X1; ATP receptor; Purinergic receptor; P2RX1; P2X1 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P51575, P51576, P47824 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | P2X purinoceptor 1 (P2RX1) is a ~44 kDa protein. ATP-gated nonselective transmembrane cation channel permeable to potassium, sodium and with relatively high calcium permeability. Furthermore, CTP functions as a weak affinity agonist for P2RX1. Plays a role a role in urogenital, immune and cardiovascular function. Specifically, plays an important role in neurogenic contraction of smooth muscle of the vas deferens, and therefore is essential for normal male reproductive function. In addition, contributes to smooth muscle contractions of the urinary bladder. 1. Bianchi, BR. et al. (1999) European journal of pharmacology 376, 127-38. PMID: 10440098 2. Egan, TM. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 3413-20. PMID: 15056721 3. Allsopp, RC. et al. (2010) The Journal of biological chemistry 285, 32770-32777. PMID: 20699225 4. Valera, S. et al. (1995) Receptors & channels 3, 283-9. PMID: 8834001 5. Evans, RJ. et al. (1996) The Journal of physiology 497 ( Pt 2), 413-22. PMID: 8961184 6. Roberts, JA. et al. (2004) The Journal of biological chemistry 279, 9043-55. PMID: 14699168 7. Lecut, C. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 2801-9. PMID: 19635923 | ||||||||
| 참고사항 | For research use only |
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