Anti-Mouse P2RX7 Polyclonal Antibody (MV713014)

Name: Anti-Mouse P2RX7 Polyclonal Antibody
Brand: abinScience
SKU: MV713014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

MV713014

설명

Anti-P2RX7 Polyclonal Antibody (MV713014) is a rabbit polyclonal antibody detecting P2X purinoceptor 7; P2X7; ATP receptor; P2Z receptor; Purinergic receptor; P2rx7; P2x7 in ELISA, IHC, WB. Suitable for Rat and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant mouse P2RX7 (Gln52-Asp329).

타겟

P2X purinoceptor 7; P2X7; ATP receptor; P2Z receptor; Purinergic receptor; P2rx7; P2x7

내독소 수준

Please contact with the lab for this information.

순도

>95% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

Q9Z1M0, Q64663

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

P2X purinoceptor 7 (P2RX7) is a ~68 kDa protein. ATP-gated nonselective transmembrane cation channel. Requires high millimolar-range concentrations of ATP to become activated. ATP binding trigers the rapid opening of the channel and allows Na(+) and Ca(2+) influx and K(+) efflux. Has also the ability to form a large pore in the cell membrane, allowing the passage of large cationic molecules. In microglia, may mediate NADPH transport across the plasma membrane.

1. Chessell, IP. et al. (1998) FEBS letters 439, 26-30. PMID: 9849870

2. Robinson, LE. et al. (2014) The Journal of biological chemistry 289, 31983-31994. PMID: 25281740

3. Karmakar, M. et al. (2016) Nature communications 7, 10555. PMID: 26877061

4. Di, A. et al. (2018) Immunity 49, 56-65.e4. PMID: 29958799

5. Yang, D. et al. (2015) Immunity 43, 923-32. PMID: 26572062

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-Mouse P2RX7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Mouse P2RX7 Polyclonal Antibody (MV713014)

개요

이미지

참고 문헌

데이터시트

SDS