Anti-PCK2 Polyclonal Antibody (HS850014)

Name: Anti-PCK2 Polyclonal Antibody
Brand: abinScience
SKU: HS850014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HS850014

설명

Anti-PCK2 Polyclonal Antibody (HS850014) is a rabbit polyclonal antibody detecting PCK2 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PCK2 (Ala292-Met640).

타겟

PEPCK-M, PEPCK2, Phosphoenolpyruvate carboxykinase [GTP], mitochondrial, PCK2

정제

Purified by antigen affinity column.

등록번호

Q16822

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Phosphoenolpyruvate carboxykinase [GTP], mitochondrial (PCK2) is a ~70 kDa protein. Mitochondrial phosphoenolpyruvate carboxykinase that catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. Can play an active role in glyceroneogenesis and gluconeogenesis. Also acts as a serine/threonine-protein kinase: phosphorylates and activates ACSL4, thereby promoting ferroptosis.

1. Escós, M. et al. (2016) Biochemistry and biophysics reports 7, 124-129. PMID: 28955899

2. Li, Z. et al. (2024) Nature chemical biology 20, 1341-1352. PMID: 38720107

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-PCK2 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-PCK2 Polyclonal Antibody (HS850014)

개요

이미지

참고 문헌

데이터시트

SDS

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