Anti-PDCD6IP Polyclonal Antibody (HV421014)

Name: Anti-PDCD6IP Polyclonal Antibody
Brand: abinScience
SKU: HV421014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
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SDS

개요

카탈로그 번호

HV421014

설명

Anti-PDCD6IP Polyclonal Antibody (HV421014) is a rabbit polyclonal antibody detecting PDCD6IP in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PDCD6IP (Glu174-Ala383).

타겟

ALG-2-interacting protein 1, ALG-2-interacting protein X, Hp95, AIP1, ALIX, KIAA1375, PDCD6IP, Programmed cell death 6-interacting protein, PDCD6-interacting protein

정제

Purified by antigen affinity column.

등록번호

Q8WUM4

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Programmed cell death 6-interacting protein (PDCD6IP) is a ~96 kDa protein. Multifunctional protein involved in endocytosis, multivesicular body biogenesis, membrane repair, cytokinesis, apoptosis and maintenance of tight junction integrity. Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway requires the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis.

1. Matsuo, H. et al. (2004) Science (New York, N.Y.) 303, 531-4. PMID: 14739459

2. Carlton, JG. et al. (2007) Science (New York, N.Y.) 316, 1908-12. PMID: 17556548

3. Morita, E. et al. (2007) The EMBO journal 26, 4215-27. PMID: 17853893

4. Carlton, JG. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 10541-6. PMID: 18641129

5. Baietti, MF. et al. (2012) Nature cell biology 14, 677-85. PMID: 22660413

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-PDCD6IP polyclonal antibody at 1ug/mL on various samples.
Lane 1: NIH3T3 cell lysate
Lane 2: Jurkat cell lysate
Lane 3: K562 cell lysate
Lane 4: PC-12 cell lysate
Lane 5: Mouse liver lysate
Lane 6: Rat liver lysate

참고 문헌

데이터시트

Anti-PDCD6IP Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-PDCD6IP Polyclonal Antibody (HV421014)

개요

이미지

참고 문헌

데이터시트

SDS