

| 카탈로그 번호 | HY442014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-PDHB Polyclonal Antibody (HY442014) is a rabbit polyclonal antibody detecting PDHB in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pongo abelii.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human PDHB (Leu31-Asn341). | ||||||||
| 타겟 | PDHB, PDHE1-B, PHE1B, Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P11177 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB) is a ~39 kDa protein. Together with PDHA1 forms the heterotetrameric E1 subunit of the pyruvate dehydrogenase (PDH) complex. The PDH complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links cytoplasmic glycolysis and the mitochondrial tricarboxylic acid (TCA) cycle (Probable). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and dihydrolipoamide dehydrogenase (E3) (Probable). The E1 subunit catalyzes both the thiamine pyrophosphate (TPP)-dependent decarboxylation of pyruvate and the reductive acetylation of a lipoyl group covalently linked to the lipoyl-bearing domains of E2. 1. Seifert, F. et al. (2007) Biochemistry 46, 6277-87. PMID: 17474719 2. Kato, M. et al. (2008) Structure (London, England : 1993) 16, 1849-59. PMID: 19081061 | ||||||||
| 참고사항 | For research use only. |
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